Assesment of serum taurine level as a potential biomarker for early diagnosis of diabetic nephropathy

Objective: Measuring of serum taurine as an early marker to detect and prevent complications Diabetic nephropathy. Method: Ninty diabetic patients (male female) were chosen from Ahmed Maher hospital after their approval, eighty classified into four groups (diabetic control group, stage before dialysis group) according its Complete clinical examination, investigation biochemical analysis, twenty controlled not suffered kidney impairment considered group. ten frank healthy non persons enrolled volunteers. analysis (liver functions, lipid profile), add measuring Blood sugar, HbA1c, the recent biomarker taurine, was measured for all patient Results: The data showed non-significant change in profile, creatinine urine, Albumine regarding group (P>0.05). that Liver function demonstrated significance between groups,but values recorded significant changes related (p<0.05). Kidney (urea – creatinine) very highly (p<0.00), except Early also, there is a blood glucose HbA1c (P>0.001). On other hand, extremely decrease severity nephropathy compared (P<0.000). Conclusion: Serum reduced with advanced conditions Taurine Level (prognostic) complications.